研究業績

2021年

Molecular cloning and characterization of common marmoset SULT1C subfamily members that catalyze the sulfation of thyroid hormones. Kurogi, K., Manabe, Y., Liu, M.-C., Suiko, M., Sakakibara, Y. Biosci. Biotechnol. Biochem. 85, 2113-2120. doi.org/10.1093/bbb/zbab141

The crystal structure of mouse SULT2A8 reveals the mechanism of 7α-hydroxyl, bile acid sulfation. Teramoto, T., Nishio, T., Kurogi, K., Sakakibara, Y., Kakuta, Y. Biochem. Biophys. Res. Commun. 562, 15-20.doi.org/10.1016/j.bbrc.2021.04.113

Proteolytic Maturation of the Outer Membrane c-Type Cytochrome OmcZ by a Subtilisin-Like Serine Protease Is Essential for Optimal Current Production by Geobacter sulfurreducens. Kai, A., Tokuishi, T., Fujikawa, T., Kawano, Y., Ueki, T., Nagamine, M., Sakakibara, Y., Suiko, M., Inoue, K. Appl. Env. Microbiol. 87, e0261720.doi.org/10.1128/AEM.02617-20

Varietal differences in flavonoid and antioxidant activity in Japanese soybean accessions. Arifin, H.A., Hashiguchi, T., Nagahama, K., Hashiguchi, M., Muguerza M., Sakakibara, Y., Tanaka, H., Akashi, R. Biosci. Biotechnol. Biochem. 85, 916-922.doi.org/10.1093/bbb/zbaa104

完熟きんかん「たまたま」の新しい機能性について -NK細胞賦活効果・抗ストレス効果・抗疲労効果- 永M清子、江藤望、有村保次、榊原陽一、水光正仁. 生物工学会誌 99, 320-322.

宮崎大学医学部附属病院臨床研究支援センター食品臨床試験部門の取り組み. 有村保次、永M清 子、黒木光歩、長友奈央、長野文子、梶原睦美、平井亜優美、榊原陽一、國武久登、竹島秀雄、片岡 寛章. 宮崎医会誌 45, 222-230.


2020年

Effects of indole and indoxyl on the intracellular oxidation level and phagocytic activity of differentiated HL-60 human macrophage cells.Tsutsumi, S., Tokunaga, Y., Shimizu, S., Kinoshita, H., Ono, M., Kurogi, K., Sakakibara, Y., Suiko, M., Liu, M.C., Yasuda, S. J. Toxicol. Sci. 45,569-579. doi.org/10.2131/jts.45.569

Investigation of the effects of indoxyl sulfate, a uremic toxin, on the intracellular oxidation level and phagocytic activity using an HL-60-differentiated human macrophage cell model. Tsutsumi, S., Tokunaga, Y., Shimizu, S., Kinoshita, H., Ono, M., Kurogi, K., Sakakibara, Y., Suiko, M., Liu, M.C., Yasuda, S. Biosci. Biotechnol. Biochem. 84, 1023-1029.doi.org/10.1080/09168451.2020.1715782

生物進化に伴う硫酸イオン代謝と代謝変換酵素の多様な生理機能. 黒木勝久、橋口拓勇、榊原陽一. 化学と生物 58, 511-519

イオウ元素に着目したプロテオミクス解析技術確立と応用. 黒木勝久、榊原陽一. 黒木勝久、橋口拓勇、榊原陽一. アグリバイオ 4, 69-70.

ヒトcytosolic sulfotransferase発現大腸菌を用いた硫酸化ポリフェノール類の部位選択的合成とその応用. 下平武彦、黒木勝久、橋口拓勇、水光正仁、榊原陽一. 硫酸と工業 73, 127-133.


2019年

Identification of zebrafish steroid sulfatase and comparative analysis of the enzymatic properties with human steroid sulfatase. Kurogi, K., Yoshihama, M., Williams, F.E., Kenmochi, N., Sakakibara, Y., Suiko, M., Liu, M.C. J. Steroid Biochem. Mol. Biol. 185, 110-117.doi.org/10.1016/j.jsbmb.2018.08.004

レトルト加工及び保蔵期間が鶏肉のイミダゾールジペプチド含有量に及ぼす影響 神力(長友)はるな、近藤知巳、永M清子、福井敬一、黒木勝久、水光正仁、榊原陽一. 日本食品科学工学会誌 66, 210-214.

完熟きんかん摂食に伴う血清βクリプトキサンチン濃度の検討 ?ランダム化非盲検非摂食同時対照群間比較試験?. 有村保次、武安智樹、米澤ゆう子、永M清子、神力はるな、近藤知巳、上野浩晶、松元信弘、江藤望、榊原陽一、水光正仁、片岡寛章. 薬理と治療 47, 65-75.

脂溶性ビタミンの硫酸抱合代謝. 橋口拓勇、黒木勝久、水光正仁、榊原陽一. ビタミン 93, 128-132.

ステロイド代謝におけるステロイド硫酸化反応の制御と生理的意義. 橋口拓勇、黒木勝久、水光正仁、榊原陽一. 硫酸と工業 72, 99-104.

宮崎大学焼酎「薫陶」に至る長い道のり. 榊原陽一. でん粉と食品 44, 38-39.


2018年

Effect of SULT2B1 genetic polymorphisms on the sulfation of dehydroepiandrosterone and pregnenolone by SULT2B1b allozymes. Alherz, F.A., El Daibani, A.A., Abunnaja, M.S., Bairam, A.F., Rasool, M.I., Sakakibara, Y., Suiko, M., Kurogi, K., Liu, M.-C. Mol Cell Endocrinol. doi: 10.1016/j.mce.2019.110535

Effects of Genetic Polymorphisms on the Sulfation of Dehydroepiandrosterone and Pregnenolone by Human Cytosolic Sulfotransferase SULT2A1. Liu, M.-C. et. al. Biochem. Cell Biol. 96, 655-662. doi: 10.1139/bcb-2017-0341.

On the Role of Genetic Polymorphisms in the Sulfation of Cholesterol by Human Cytosolic Sulfotransferase SULT2B1b. Alherz, F.A., El Daibani, A.A., Bairam, A.F., Abunnaja. M.S., Rasool, M.I., Kurogi, K., Sakakibara, Y., Suiko, M., Liu, M.-C. J. Biochem. 164, 215-221. doi: 10.1093/jb/mvy042.

The critical role of His48 in mouse cytosolic sulfotransferase SULT2A8 for the 7α-hydroxyl sulfation of bile acids. Shimohira, T., Kurogi, K., Liu, M.-C., Suiko, M., Sakakibara, Y. Biosci. Biotechnol. Biochem. 82, 1359-1364. doi: 10.1080/09168451.2018.1464897.

Sulfation of catecholamines and serotonin by SULT1A3 allozymes. Bairam, A.F., Rasool, M.I., Alherz, F.A., Abunnaja, M.S., El Daibani, A.A., Gohal, S.A., Kurogi, K., Sakakibara, Y., Suiko, M., Liu, M.-C. Biochem. Pharmacol. Biochem. 151, 104-113. doi: 10.1016/j.bcp.2018.03.005.

Radical Scavenging Effects of 1-Naphthol, 2-Naphthol, and Their Sulfate-conjugates. Sugahara, S., Fukuhara, K., Tokunaga, Y., Tsutsumi, S., Ueda, Y., Ono, M., Kurogi, K., Sakakibara, Y., Suiko, M., Liu, M.-C., Yasuda, S. J. Toxicol. Sci. 43,213-221. doi: 10.2131/jts.43.213.

Effects of Human SULT2A1 Genetic Polymorphisms on the Sulfation of Tibolone. Miller, E., Zalzala, M.H., Abunnaja, M.S., Kurogi, K., Sakakibara, Y., Suiko, M., Liu, M.-C. Eur. J. Drug Metab. Pharmacokinetics Acccepted for Publication. doi: 10.1007/s13318-017-0458-2.


2017年

完熟きんかん摂食に伴う抗疲労効果の検討–ランダム化非盲検非摂食同時対照比較群間試験–. 武安智樹、有村保次、永M清子、神力はるな、榊原陽一、水光正仁、片岡寛章. 薬理と治療 45, 1967-1975.

疲労感を有する健常人に対する完熟きんかんの有効性を探索する非対照・非盲検試験. 永M清子、有村保次、神力はるな、米澤ゆう子、松尾彩子、上野浩晶、松元信弘、江藤望、榊原陽一、水光正仁、片岡寛章. 薬理と治療 45, 1831-1842.

Human Cytosolic Sulphotransferase SULT1C3: genomic analysis and functional characterization of splice variant SULT1C3a and SULT1C3d. Kurogi, K., Shimohira, T., Kouriki-Nagatomo, H., Zhang, G., Miller, E.R., Sakakibara, Y., Suiko, M., Liu, M.-C. J. Biochem. 162, 403-414. doi: 10.1093/jb/mvx044.

Structure basis for the broad substrate specificity of the human tyrosylprotein sulfotransferase-1. Tanaka, S., Nishiyori, T., Kojo, H., Otsubo, R., Tsuruta, M., Kurogi, K., Liu, M.-C., Suiko, M., Sakakibara, Y., Kakuta, Y. Sci. Rep. 7,8776. doi:10.1038/s41598-017-07141-8

Identification and characterization of 5α-cyprinol-sulfating cytosolic sulfotransferases (Sults) in the Zebrafish (Danio rerio). Kurogi, K, Yoshihama, M., Horton, A., Schiefer, I.T., Krasowski, M.D., Hagey, L.R., Williams, F.E., Sakakibara, Y., Kenmochi, N., Suiko, M., Liu, M.C. J. Steroid Biochem. Mol. Biol. 174,120-127. doi: 10.1016/j.jsbmb.2017.08.005.

Δ4-3-Ketosteroids as a New Class of Substrates for the Cytosolic Sulfotransferases. Hashiguchi T, Kurogi, K., Shimohira, T., Teramoto, T., Liu, M.C., Suiko, M., Sakakibara, Y. Biochim. Biophys. Acta. 1861,2883-2890. doi: 10.1016/j.bbagen.2017.08.005.

Sulfation of vitamin D3-related compounds: Identification and characterization ofthe responsible human cytosolic sulfotransferases. Kurogi, K., Sakakibara, Y., Suiko M, Liu MC. FEBS Lett. 591,2417-2425. doi: 10.1002/1873-3468.12767.

Identification and Characterization of the Zebrafish Glutathione S-Transferase Pi-1. Abunnaja, M.S., Kurogi, K., Mohammed Y.I., Sakakibara, Y., Suiko, M., Hassoun, E.A., Liu, M.-C. J. Biochem. Mol. Toxicol. 31(10). doi: 10.1002/jbt.21948.

機能性食品開発のための初期評価試験プロトコール集 山本(前田)万里(監修)シーエムシー出版、第V編 成分単離・同定・作用機序解析:第2章作用機序解析、黒木勝久、黒木(平山)未央、榊原陽一(一部分筆担当)

食品成分の複合的な抗酸化活性の評価について 近藤知巳、上橋朋佳、渡辺朋子、河野朝美、黒木勝久、福井敬一、水光正仁、榊原陽一  日本食品科学工学会誌 64巻、9号 457-463. doi: 10.3136/nskkk.64.457

Characterization of a novel allergenic protein from the octocoral Scleronephthya gracillima (Kuekenthal) that corresponds to a new GFP-like family named Akane. Kato, Y., Jimbo, M., Sakakibara, Y., Onizuka, R., Takahashi, T., Matsuhashi, S., Mita, H., Amada, K., Imahara, Y., Tanabe, K., Toda, A., Kamiya, H. Luminescence 32,1009-1016. doi: 10.1002/bio.3284.

Regioselective production of sulfated polyphenols using human cytosolic sulfotransferase (SULT)-expressing Escherichia coli cells. Shimohira, T., Kurogi, K., Hashiguchi, T., Liu, M.-C., Suiko, M., Sakakibara, Y. J. Biosci. Bioeng. 124,84-90. doi: 10.1016/j.jbiosc.2017.02.006.

A substrate-bound structure of cyanobacterial biliverdin reductase identifies stacked substrates as critical for activity. Takao, H., Hirabayashi, K., Nishigaya, Y., Kouriki, H., Nakaniwa, T., Hagiwara, Y., Harada, J., Sato, H., Yamazaki, T., Sakakibara, Y., Suiko, M., Asada, Y., Takahashi, Y., Yamamoto, K., Fukuyama, K., Sugishima, M., Wada, K. Nature Commun. DOI: 10.1038/ncomms14397

Ubiquitin-Proteasome Dependent Regulation of the GOLDEN2-LIKE 1 Transcription Factor in Response to Plastid Signals. Tokumaru, M., Adachi, F., Toda, M., Ito-Inaba, Y., Yazu, F., Hirosawa, Y., Sakakibara, Y., Suiko, M., Kakizaki, T., Inaba, T. Plant Physiol. 173, 524-535.

Updated perspectives on the cytosolic sulfotransferases (SULTs) and SULT-mediated sulfation. Suiko, M., Kurogi, K., Hashiguchi, T., Sakakibara, Y., Liu, M.-C. Biosci. Biotechnol. Biochem. 81, 63-72.


2016年

A proteomic approach for the analysis of S-nitrosylated proteins using a fluorescence labeling technique. Yoshimura, T., Kurogi, K., Liu, M.-C., Suiko, M., Sakakibara, Y. J. Electrophoresis 60, 5-14.

Human Cytosolic Sulfotransferase SULT1A3 Mediates the Sulfation of Dextrorphan. Yamamoto, A., Kurogi, K., Schiefer, I.T., Liu, M.-Y., Sakakibara, Y., Suiko, M., Liu, M.-C. Biol. Pharm. Bull. 39, 1432-1436.

Identification and Characterization of the Human Cytosolic Sulfotransferases Mediating the Sulfation of Clioquinol and Iodoquinol. Yamamoto, A., Debrah-Pinamang, M., DiModica, N.J., Kurogi, K., Naqvi, A.A., Hui, Y., Sakakibara, Y., Suiko, M., Liu, M.-C. Drug Metab. Lett. 10, 200-205.

植物硫酸転移酵素の諸性質と今後の展開, 橋口拓勇, 榊原陽一, 黒木勝久, 水光正仁  日本農薬学会誌 41, 198-202.

昆布の抗酸化作用 白杉 一郎,松井 隆史,伝宝 啓史,黒木 勝久,榊原 陽一,水光 正仁  New Food Industry 58,(6)

A novel procedure for the assessment of the antioxidant capacity of food components. Yoshimura, T., Harashima, M., Kurogi, K., Suiko, M., Liu, M.-C., Sakakibara, Y. Anal. Biochem. 507, 7-12.

Sulfate Conjugation of Daphnetin by the Human Cytosolic Sulfotransferases. Han, Z., Xi, Y., Luo, L., Zhou, C., Kurogi, K., Sakakibara, Y., Suiko, M., Liu, M.-C. J. Ethnopharmacol. S0378-8741, 30311-30317.

シイタケおよびその加工品による抗酸化ストレス作用 近藤知巳, 中島有紀子, 渡辺朋子, 吉山佳世, 内田飛香, 黒木勝久, 福井敬一, 水光正仁, 榊原陽一 日本食品科学工学会誌 63, 199-208.

Human cytosolic sulfotransferase SULT1C4 mediates the sulfation of doxorubicin and epirubicin. Luo, L., Zhou, C., Hui, Y., Kurogi, K., Sakakibara, Y., Suiko, M., Liu, M.-C. Drug Metab. Pharmacokinet. 31, 163-166.

Sulfation of 6-Gingerol by the Human Cytosolic Sulfotransferases: A Systematic Analysis. Luo L, Mei, X., Xi, Y., Zhou, C., Hui, Y., Kurogi, K., Sakakibara, Y., Suiko, M., Liu, M.-C. Planta Med. 82, 238-243.

Sulfation of benzyl alcohol by the human cytosolic sulfotransferases (SULTs): a systematic analysis. Zhang, L., Kurogi, K., Liu, M.-Y., Schnapp, A.M., Williams, F.E., Sakakibara, Y., Suiko, M., Liu, M.-C. J. Appl. Toxicol. 36, 1090-1094.


2015年

Sulfation of 6-hydroxymelatonin, N-acetylserotonin and 4-hydroxyramelteon by the human cytosolic sulfotransferases (SULTs). Luo, L., Zhou, C., Kurogi, K., Sakakibara, Y., Suiko, M., Liu, M.-C. Xenobiotica 46, 612-619.

Sulfation of afimoxifene, endoxifen, raloxifene, and fulvestrant by the human cytosolic sulfotransferases (SULTs): A systematic analysis. Hui, Y., Luo, L., Zhang, L., Kurogi, K., Zhou, C., Sakakibara, Y., Suiko, M., Liu, M.-C. J. Pharmacol. Sci., 128, 144-149.

Sulphation of acetaminophen by the human cytosolic sulfotransferases: a systematic analysis. Yamamoto, A., Liu, M.-Y., Kurogi, K., Sakakibara, Y., Saeki, Y., Suiko, M., Liu, M.-C. J. Biochem., 158, 497-504.

タンパク質標識技術を用いたS-ニトロシル化タンパク質の解析法開発, 芳村俊広、黒木勝久、水光正仁、榊原陽一  電気泳動 89, 123-125.

Effect of kumquat (Fortunella crassifolia) pericarp on natural killer cell activity in vitro and in vivo. Nagahama, K., Eto, N., Shimojo, T., Kondoh, T., Nakahara, K., Sakakibara, Y., Fukui, K., Suiko, M. Biosci. Biotechnol. Biochem., 79, 1327-1336.

Analysis of expressed proteins in the pollen tube occurring self-incompatible response using mass or single-culture system of mature pollen in citrus. Abe, A., Uchida, A., Hoshino, Y., Sakakibara, Y., Suiko, M., Kunitake, H. Acta Horticulturae, 1065, 1267-1274.


2014年

Sulfation of phenylephrine by the human cytosolic sulfotransferases. Yamamoto, A., Kim, J., Liu, M.-Y., Kurogi, K., Sakakibara, Y., Suiko, M., Liu, M.-C. Drug Metab. Lett., 8, 96-100.

Delta-tocotrienol induces apoptotic cell death via depletion of intracellular squalene in ED40515 cells. Yamasaki, M., Nishimura, M., Sakakibara, Y., Suiko, M., Morishita, K., Nishiyama, K. Food Funct., 5, 2842-2849.

The importance of 1,2-dithiolane structure in α-lipoic acid for the downregulation of cell surface β1-integrin expression of human bladder cancer cells. Yamasaki, M., Soda, S., Sakakibara, Y., Suiko, M., Nishiyama, K. Biosci. Biotechnol. Biochem., 78, 1939-1942.

Sulfation of opioid drugs by human cytosolic sulfotransferases: Metabolic labeling study and enzymatic analysis. Kurogi, K., Chepak, A., Hanrahan, M.T., Liu, M.Y., Sakakibara, Y., Suiko, M., Liu, M.C. Eur. J. Pharm. Sci., 62, 40-48

α-Lipoic acid suppresses migration and invasion via downregulation of cell surface β1-integrin expression in bladder cancer cells. Yamasaki, M., Iwase, M., Kawano, K., Sakakibara, Y., Suiko, M., Ikeda, M., Nishiyama, K. J. Clin. Biochem. Nutr.,54,18-25.

Identification of a novel flavonoid glycoside sulfotransferase in Arabidopsis thaliana. Hashiguchi, T., Sakakibara, Y., Shimohira, T., Kurogi, K., Yamasaki, M., Nishiyama, K., Akashi, R., Liu, M.C., Suiko, M. J. Biochem.,155,91-97.

Oligomeric proanthocyanidins from rabbiteye blueberry leaves inhibits the proliferation of human T-cell lymphotropic virus type 1-associated cell lines via apoptosis and cell cycle arrest. Nagahama K, Eto, N., Sakakibara, Y., Matsusita, Y.I., Sugamoto, K., Morishita, K., Suiko, M. J. Func. Foofs ,6,356-366.


2013年

Induction of apoptotic cell death in HL-60 cells by jacaranda seed oil derived fatty acids. Yamasaki, M., Motonaga, C., Yokoyama, M., Ikezaki, A., Kakihara, T., Hayasegawa, R., Yamasaki, K., Sakono, M., Sakakibara, Y., Suiko, M., Nishiyama, K.. J. Oleo Sci.,62, 925-932.

The use of zebrafish as a model system for investigating the role of the SULTs in the metabolism of endogenous compounds and xenobiotics. Kurogi K, Liu TA, Sakakibara Y, Suiko M, Liu MC. Drug Metab Rev. ,45,431-440.

Identification and characterization of a novel kaempferol sulfotransferase from Arabidopsis thaliana. Hashiguchi T, Sakakibara Y, Hara Y, Shimohira T, Kurogi K, Akashi R, Liu MC, Suiko M. Biochem Biophys Res Commun.,434, 829-835.

Genistein induces apoptotic cell death associated with inhibition of the NF-κB pathway in adult T-cell leukemia cells. Yamasaki, M., Mine, Y., Nishimura, M., Fujita, S., Sakakibara, Y., Suiko, M., Morishita, K., Nishiyama, K. Cell Biol. Int.,37,742-747.

Crystal structure of human tyrosylprotein sulfotransferase-2 reveals the mechanism of protein tyrosine sulfation reaction. Teramoto, T., Fujikawa, Y., Kawaguchi, Y., Kurogi, K., Soejima, M.,Adachi, R., Nakanishi, Y., Mishiro-Sato, E., Liu, M.-C., Sakakibara, Y., Suiko, M.,Kimura, M., Kakuta, Y. Nat. Commun.,4,1572.


2012年

Ethanol sulfation by the human cytosolic sulfotransferases: A systematic analysis. Kurogi, K., Davidson, G., Mohammed, Y.I., Williams, F.E., Liu, M.Y., Sakakibara, Y., Suiko, M., and Liu, M.-C. Bio. Pharm. Bull., 35, 2180-2185.

Conjugated linoleic acids inhibit hypoxia inducible factor-1α stabilization under hypoxic condition in human hepatocellular carcinoma cells. Yamasaki, M., Nagatomo, T., Matsuyama, T., Ikeho, Y., Kato, E., Nishiyama, K., Sakakibara, Y., Suiko, M., Nishiyama, K. J. Oleo Sci.,61,491-496.

Sulfation of buprenorphine, pentazaocine, and naloxone by human cytosolic sulfotransferases. Kurogi, K., Chen, M., Lee, Y., Shi, B., Yang, T., Liu, M.Y., Sakakibara, Y., Suiko, M., and Liu, M.-C. Drug Metab. Lett.,6, 109-115.

Concerted actions of the catechol O-methyltransferase and the cytosolic sulfotransferase SULT1A3 in the metabolism of catecholic drugs. Kurogi, K., Alazizi, A., Liu, M.Y., Sakakibara, Y., Suiko, M., Sugahara, T., and Liu, M.-C. Biochem. Pharmacol.,84, 1186-1195.

Selective inhibition by apocynin of the proliferation and adhesion to fibronectin of v-H-ras-transformed 3Y1 cells. Yamasaki, M., Iwase, M., Kawano, K., Sakakibara, Y., Suiko, M., Nishiyama, K. Biosci. Biotechnol. Biochem.,76,1177-1181.

Sulfation of ractopamine and salbutamol by the human cytosolic sulfotransferases. Ko, K.*, Kurogi, K.*, Davidson, G., Liu, M.Y., Sakakibara, Y., Suiko, M., and Liu, M.-C. J. Biochem.,152, 275-283. (*These two authors contributed equally to this work.)

Alpha lipoic acid selectively inhibits proliferation and adhesion to fibronectin of v-H-ras-transformed 3Y1 cells. Yamasaki, M., Iwase, M., Kawano, K., Sakakibara, Y., Suiko, M., Nishiyama, K. J. Clin. Biochem. Nutr. ,50,234-240.

Identification of self-incompatibility related proteins in the pistil of Japanese pear (Pyrus pyrifolia (Burm.f.)) by proteome analysis. Uchida, A., Sassa, H., Takenaka, S., Sakakibara, Y., Suiko, M., Kunitake, H. Plant Omics J., 5, 320-325.

Comprehensive analysis of expressed proteins in the different stage of the style development of self-incompatible 'Hyuganatsu' (Citrus tamurana hort. ex Tanaka).  Uchida, A., Takenaka, S., Sakakibara, Y., Kurogi, S., Honsho, C., Sassa, H., Suiko, M., Kunitake, H. J. Jap. Soc. for Horticul. Sci.,81,150-158.

Identification and characterization of zebrafish SULT1 ST9, SULT3 ST4, and SULT3 ST5. Mohammed, Y.I., Kurogi, K., Shaban, A.A., Xu, Z., Liu, M.-Y., Williams, F.E., Sakakibara, Y., Suiko, M., Bhuiyan, S., Liu, M.-C. Aquat. Toxicol.,112-113, 11-18.

タンパク質の翻訳後修飾としてのチロシン硫酸化, 水光正仁、榊原陽一 バイオサイエンスとインダストリー, 70,201-205.


2011年

A comparative study of the sulfation of bile acids and a bile alcohol by the Zebra danio (Danio rerio) and human cytosolic sulfotransferases (SULTs). Kurogi, K., Krasowski, M.D., Injeti, E., Liu, M.-Y., Williams, F.E., Sakakibara, Y., Suiko, M., Liu, M.-C. J.Steroid Biochem. Mol. Biol.,127, 307-314.

Efficient approach for simultaneous estimation of the multiple health-promoting effects of foods. Nagahama, K., Eto, N., Yamamori, K., Nishiyama, K., Sakakibara, Y., Iwata, T., Uchida, A., Yoshihara, I., Suiko, M. J. Agric. Food Chem.,59, 8575-8588.

Enzymatic sulfation of tocopherols and tocopherol metabolites by human cytosolic sulfotransferases. Hashiguchi, T., Kurogi, K., Sakakibara, Y.Yamasaki, M., Nishiyama, K., Yasuda, S., Liu, M.-C., Suiko, M. Biosci. Biotechnol. Biochem.,75, 1951-1956.

Inhibition of proliferation by agricultural plant extracts in seven human adult T-cell leukaemia (ATL)-related cell lines. Kai, H., Akamatsu, E., Torii, E., Kodama, H., Yukizaki, C., Sakakibara, Y., Suiko, M., Morishita, K., Kataoka, H., Matsuno, K. J. Nat. Med.,65, 651-655.

Sulfation of chlorotyrosine and nitrotyrosine by human lung endothelial and epithelial cells: Role of the human SULT1A3.  Yasuda, S., Yasuda, T., Liu, M.-Y., Shetty, S., Idell, S., Boggaram, V., Suiko, M., Sakakibara, Y., Fu, J., Liu, M.-C. Toxicol. Appl. Pharmacol.,251, 104-109.

Identification, characterization, and ontogenic study of a catechol O-methyltransferase from zebrafish. Alazizi, A., Liu, M.-Y., Williams, F.E., Kurogi, K., Sakakibara, Y., Suiko, M., Liu, M.-C. Aquat. Toxicol.,102, 18-23.

中国餅麹(曲)由来の新規黒色系糸状菌の焼酎醸造特性 野崎直樹, 中原徳昭, 山本英樹, 榊原陽一, 林幸男, 小川喜八郎, 水光正仁.  日本生物工学会誌,89, 20-26.

プロテオーム解析による食品機能の研究 榊原陽一、中原幸太、森永浩通、山崎正夫、西山和夫、水光正仁. 日本生物工学会誌, 89, 593-596.

食品成分の網羅的機能性評価法 江藤望, 山森一人, 永濱清子, 榊原陽一, 西山和夫, 吉原郁夫, 水光正仁. 日本生物工学会誌, 89, 589-592.

薬物代謝と農薬の効能:特に硫酸化について 橋口拓勇, 榊原陽一, 水光正仁. 日本農薬学会誌, 36, 297-299.


2010年

Novel screening method for potential skin-whitening compounds by a luciferase reporter assay. Shirasugi, I., Sakakibara, Y., Yamasaki, M., Nishiyama, K., Matsui, T., Liu, M.-C., Suiko, M. Biosci. Biotechnol. Biochem.,74, 2253-2258.

Genistein induced apoptotic cell death in adult T-cell leukemia cells through estrogen receptors. Yamasaki, M., Mukai, A., Ohba, M., Mine, Y., Sakakibara, Y., Suiko, M., Morishita, K., Nishiyama, K. Biosci. Biotechnol. Biochem.,74, 2113-2115.

Zebrafish as a Model for the Study of the Phase II Cytosolic Sulfotransferases. Liu, T.A., Bhuiyan, S., Liu, M.-Y., Sugahara, T., Sakakibara, Y., Suiko, M., Yasuda, S., Kakuta, Y., Kimura, M., Williams, F.E., Liu, M.-C. Curr. Drug Metab.,11, 538-546.

Mouse cytosolic sulfotransferase SULT2B1b interacts with cytoskeletal proteins via a proline/serine-rich C-terminus. Kurogi, K., Sakakibara, Y., Kamemoto, Y., Takahashi, S., Yasuda, S., Liu, M.-C., Suiko, M. FEBS J.,277, 3804-3811.

Sulfation of drug compounds by the zebrafish cytosolic sulfotransferases (SULTs). Kurogi, K., Dillon, J., Nasser, A., Liu, M.-Y., Williams, F.E., Sakakibara, Y., Suiko, M., Liu, M.-C. Drug Metab. Lett.,4, 62-68.

Identification of a novel biomarker for oxidative stress induced by hydrogen peroxide in primary human hepatocytes using the 2-nitrobenzenesulfenyl chloride isotope labeling method. Takami, Y., Uto, H., Tamai, T., Sato, Y., Ishida, Y., Morinaga, H., Sakakibara, Y., Moriuchi, A., Oketani, M., Ido, A., Nakajima, T., Okanoue, T., Tsubouchi, H. Hepatol. Res.,40, 438-445.

Sulforaphane inhibited melanin synthesis by regulating tyrosinase gene expression in B16 mouse melanoma cells. Shirasugi, I., Kamada, M., Matsui, T., Sakakibara, Y., Liu, M.-C., Suiko, M. Biosci. Biotechnol. Biochem.,74, 579-582.

Molecular cloning and characterization of a novel canine sulfotransferase Kurogi, K., Sakakibara, Y., Yasuda, S., Liu, M.-C., Suiko, M. Animal Cell Technology: Basic & Applied Aspects.,16, 221-229.

スルフォラファンのメラニン産生抑制機構 白杉一郎, 鎌田美友貴, 松井隆史, 榊原陽一, 水光正仁. New Food Industry,52, 1-7.


2009年

A novel hydroxysteroid-sulfating cytosolic sulfotransferase, SULT3 ST3, from zebrafish: Identification, characterization, and ontogenic study.  Yasuda, S., Burgess, M., Yasuda, T., Liu, M.-Y., Bhuiyan, S., Williams, F.E., Kurogi, K., Sakakibara, Y., Suiko, M., Liu, M.-C. Drug Metab. Lett.,3, 217-227.

Mustard oil in "shibori daikon" a variety of japanese radish, selectively inhibits the proliferation of H-ras-transformed 3Y1 cells. Yamasaki, M., Omi, Y., Fujii, N., Ozaki, A., Nakama, A., Sakakibara, Y., Suiko, M., Nishiyama, K. Biosci. Biotechnol. Biochem.,73, 2217-2221.

On the similar spatial arrangement of active site residues in PAPS-dependent and phenolic sulfate-utilizing sulfotransferases. Teramoto, T., Adachi, R., Sakakibara, Y., Liu, M.-C., Suiko, M., Kimura, M.,Kakuta, Y. FEBS Lett., 583, 3091-3094.

Concerted action of the cytosolic sulfotransferase, SULT1A3, and catechol-O-methyltransferase in the metabolism of dopamine in SK-N-MC human neuroblastoma cells. Yasuda, S., Yasuda, T., Hui, Y., Liu, M.-Y., Suiko, M., Sakakibara, Y., Liu M.-C. Neurosci. Res.,64, 273-279.

Molecular cloning, expression, and characterization of a novel mouse SULT6 cytosolic sulfotransferase. Takahashi, S., Sakakibara, Y., Mishiro, E., Kouriki, H., Nobe, R., Kurogi, K., Yasuda, S., Liu, M.-C., Suiko, M. J. Biochem.,146, 399-405.

A target-specific approach for the identification of tyrosine-sulfated hemostatic proteins. Liu, T.A., Yasuda, S., Williams, F.E., Liu, M.-Y., Suiko, M., Sakakibara, Y., Yang, Y.S., Liu, M.-C. Anal. Biochem., 390, 88-90.

Snapshot of a Michaelis complex in a sulfuryl transfer reaction: Crystal structure of a mouse sulfotransferase, mSULT1D1, complexed with donor substrate and accepter substrate. Teramoto, T., Sakakibara, Y., Liu, M.-C., Suiko, M., Kimura, M., Kakuta, Y. Biochem. Biophys. Res. Commun.,383, 83-87.

Dihydro-alpha-lipoic acid has more potent cytotoxicity than alpha-lipoic acid. Yamasaki, M., Kawabe, A., Nishimoto, K., Madhyastha, H., Sakakibara, Y., Suiko, M., Okamoto, T., Suda, T., Uehira, K., Nishiyama, K. In Vitro Cell Dev. Biol. Anim.,45, 275-280.

Structural basis for the broad range substrate specificity of a novel mouse cytosolic sulfotransferase--mSULT1D1. Teramoto, T., Sakakibara, Y., Liu, M.-C., Suiko, M., Kimura, M., Kakuta, Y. Biochem. Biophys. Res. Commun.,379, 76-80.

硫酸転移酵素が持つ多様な生理機能 榊原陽一, 安田伸, 水光正仁. ドージンニュース, 129, 1-6.

疾病環境における硫酸転移酵素とそのはたらき 安田伸, 榊原陽一, 水光正仁. バイオサイエンスとインダストリー,67, 19-23.


2008年

Crystal structure of SULT1D1, a mouse catecholamine sulfotransferase. Teramoto, T., Sakakibara, Y., Inada, K., Liu M.-C., Suiko, M., Kimura, M., Kakuta, Y. FEBS Lett.,582, 3909-3914.

抗変異原活性をもつ宮崎県産農産物の探索. 岩田喬子, 榊原陽一, 赤松絵奈, 酒井美穂, 柚木崎千鶴子, 山崎正夫, 西山和夫, 水光正仁.  宮崎大学農学部研究報告,54, 69-76.

Identification and characterization of two novel cytosolic sulfotransferases, SULT1 ST7 and SULT1 ST8, from zebrafish. Liu, T.A., Bhuiyan, S., Snow, R., Yasuda, S., Yasuda, T., Yang, Y.S., Williams, F.E., Liu, M.-Y., Suiko, M., Carter, G., Liu, M.-C. Aquat. Toxicol.,89, 94-102.

Characterization and ontogenic study of novel steroid-sulfating SULT3 sulfotransferases from zebrafish. Yasuda, T., Yasuda, S., Williams, F.E., Liu, M.-Y., Sakakibara, Y., Bhuiyan, S., Snow, R., Carter, G., Liu, M.-C. Mol. Cell. Endocrinol.,294, 29-36.

家蚕の硫酸転移酵素. 山本幸治, 榊原陽一, 水光正仁, Liu, M.-C., 伴野豊, 麻生陽一.  Entomatech,32, 59-61.

Molecular cloning, expression, and characterization of mouse amine N-sulfotransferases. Takahashi, S., Sakakibara, Y., Mishiro, E., Kouriki, H., Nobe, R., Kurogi, K., Yasuda, S., Liu, M.-C., Suiko, M. Biochem. Biophys. Res. Commun.,375, 531-535.

inserted by FC2 system